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Active Avoidance

Description: The active avoidance task is a fear-motivated associative avoidance test based on electric current as a source of punishment. In this task the mouse has to learn to predict the occurrence of an aversive event based on the presentation of a specific stimulus, in order to avoid the aversive event by actively moving to a different compartment. The measures recorded, number of avoidances (the mouse crossing to the other compartment during the stimulus signal), number of non-responses (the mouse failing to cross to the other compartment during the trial), response latency (latency to avoid or escape), serve as an index of learning and allows memory to be assessed.

Purpose: This task provides a simple way to assess associative learning and memory. The active avoidance task is designed to test the ability of the mouse to avoid an aversive event by learning to perform a specific behavior in response to a stimulus cue.

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Active Avoidance

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